Ive seen vortec 305's take on 350's... You might not get this engine that good but im sure you'll learn a thing or two in the process and it will be pretty fun. I shoved a 350 into my 1989 gmc s15 4x4 truck, and it was pretty fun.

I wouldnt put it into a ford because it could become a living hell, nothing will go easy there (engine mounts, everything else!). I would find some junker car or truck thats a gm product and shove it in there... I highly recommend a s10 or s15, bolts right in (for the 4.6 litre version). You will be able to rip up the streets with ease.