usually yes and sometimes its the other way around, they say it will fit and then it doesnt, just get the right size as in 4x6 then when you get them if they dont fit, make them fit

there usualy isnt all that much for mods involved.
as for the two vs one, i run one ten and it will beat pretty much any car with two run of the mill 12's using the same power, mind you the box has alot to do with it, but i switched from a good 12 to a really really good 10 and the ten murders what i used to run, even if its running on less power. More often then not i compete again cars with 2 12s using the same or more power then me and its not often i get beat.