after a quick search on the net, crutchfield recommends 8guage power wire for that amp. 12 is too small imo. you could probably get away with 10 if you were placing the amp really close to the battery, but since its a van i'm gonna presume you're gonna be running the cable quite some distance. don't starve your amp for power, or you'll regret it. in this case, you're better to go too big than too small.
for the fuse, look at the fuses on the amp (15Ax2, so 30A) and add a bit more for some headroom. so somewhere between 35-40A fuse.
here's a good reference:
Recommended Power and Ground Cable Sizes