The best of both worlds, i have a 05 ram 1500 with 4 12" premiere low pro subs in sealed box, amp is an old school orion hcca 150R, 2 farid cap,audio control 4 in 1 xover line driver, i get great SQ, it sounds great and hits hard real hard. so dont let any1 tell you you cant get SQ and SPL. You first need a good SQ amp and SQ speakers or its not going to happen for you.
I would spend the big bucks on front stage speakers and head unit, as IMO these two are the most important things for SQ, and make sure install is done right.